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In brief, bilateral maxillary and mandibular second molars were both tied with 5-0 silk ligatures for 14 days to induce periodontitis

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Flow cytometric analysis of apoptosis The 12-well plates were seeded with good cells plastered overnight (5 × 10 5 cells/well), and VC, EFP-2 in concentration gradient, and 1.2 Mm H 2 O 2 were added